![Frontiers | The RANK/RANKL/OPG system and tumor bone metastasis: Potential mechanisms and therapeutic strategies Frontiers | The RANK/RANKL/OPG system and tumor bone metastasis: Potential mechanisms and therapeutic strategies](https://www.frontiersin.org/files/Articles/1063815/fendo-13-1063815-HTML/image_m/fendo-13-1063815-g001.jpg)
Frontiers | The RANK/RANKL/OPG system and tumor bone metastasis: Potential mechanisms and therapeutic strategies
![Water extract of tendril of Cucurbita Moschata Duch. suppresses RANKL-induced osteoclastogenesis by down-regulating p38 and ERK signaling Water extract of tendril of Cucurbita Moschata Duch. suppresses RANKL-induced osteoclastogenesis by down-regulating p38 and ERK signaling](https://www.medsci.org/v17/p0632/ijmsv17p0632g005.jpg)
Water extract of tendril of Cucurbita Moschata Duch. suppresses RANKL-induced osteoclastogenesis by down-regulating p38 and ERK signaling
![SciELO - Brasil - RANK/RANKL/OPG Expression in Rapid Maxillary Expansion RANK/RANKL/OPG Expression in Rapid Maxillary Expansion SciELO - Brasil - RANK/RANKL/OPG Expression in Rapid Maxillary Expansion RANK/RANKL/OPG Expression in Rapid Maxillary Expansion](https://minio.scielo.br/documentstore/1806-4760/Qj6yZLYx7QNcxn4SbrcdRrf/a78d2380ed312d5afe4d12c0da44a13cad0f2b78.jpg)
SciELO - Brasil - RANK/RANKL/OPG Expression in Rapid Maxillary Expansion RANK/RANKL/OPG Expression in Rapid Maxillary Expansion
![RANKL-binding peptide promotes ectopic bone formation induced by BMP-2 gene transfer in murine gastrocnemius muscle RANKL-binding peptide promotes ectopic bone formation induced by BMP-2 gene transfer in murine gastrocnemius muscle](https://www.oatext.com/img/DOMR-6-327-g001.gif)
RANKL-binding peptide promotes ectopic bone formation induced by BMP-2 gene transfer in murine gastrocnemius muscle
![The RANK / RANKL system. RANKL produced by osteoblasts binds to RANK on... | Download Scientific Diagram The RANK / RANKL system. RANKL produced by osteoblasts binds to RANK on... | Download Scientific Diagram](https://www.researchgate.net/publication/279828512/figure/fig2/AS:369292248928257@1465057541103/The-RANK-RANKL-system-RANKL-produced-by-osteoblasts-binds-to-RANK-on-the-surface-of.png)
The RANK / RANKL system. RANKL produced by osteoblasts binds to RANK on... | Download Scientific Diagram
![Soluble RANKL contributes to osteoclast formation in adult mice but not ovariectomy-induced bone loss | Nature Communications Soluble RANKL contributes to osteoclast formation in adult mice but not ovariectomy-induced bone loss | Nature Communications](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41467-018-05244-y/MediaObjects/41467_2018_5244_Fig1_HTML.png)
Soluble RANKL contributes to osteoclast formation in adult mice but not ovariectomy-induced bone loss | Nature Communications
![JCI Insight - Osteocyte RANKL is required for cortical bone loss with age and is induced by senescence JCI Insight - Osteocyte RANKL is required for cortical bone loss with age and is induced by senescence](https://df6sxcketz7bb.cloudfront.net/manuscripts/138000/138815/medium/jci.insight.138815.ga.jpg)
JCI Insight - Osteocyte RANKL is required for cortical bone loss with age and is induced by senescence
![SciELO - Brasil - RANK/RANKL/OPG Expression in Rapid Maxillary Expansion RANK/RANKL/OPG Expression in Rapid Maxillary Expansion SciELO - Brasil - RANK/RANKL/OPG Expression in Rapid Maxillary Expansion RANK/RANKL/OPG Expression in Rapid Maxillary Expansion](https://minio.scielo.br/documentstore/1806-4760/Qj6yZLYx7QNcxn4SbrcdRrf/fae2aefa2d0c1a02afd08cbadd63d320cff305fa.jpg)
SciELO - Brasil - RANK/RANKL/OPG Expression in Rapid Maxillary Expansion RANK/RANKL/OPG Expression in Rapid Maxillary Expansion
![Niloticin inhibits osteoclastogenesis by blocking RANKL–RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways - ScienceDirect Niloticin inhibits osteoclastogenesis by blocking RANKL–RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0753332222002918-gr6.jpg)
Niloticin inhibits osteoclastogenesis by blocking RANKL–RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways - ScienceDirect
![RANKL gene silencing using a chitosan nanoparticle. The nanoparticle is... | Download Scientific Diagram RANKL gene silencing using a chitosan nanoparticle. The nanoparticle is... | Download Scientific Diagram](https://www.researchgate.net/publication/353305668/figure/fig4/AS:1046422937931782@1626498078942/RANKL-gene-silencing-using-a-chitosan-nanoparticle-The-nanoparticle-is-made-of-a-siRNA.png)
RANKL gene silencing using a chitosan nanoparticle. The nanoparticle is... | Download Scientific Diagram
![Spi-C positively regulates RANKL-mediated osteoclast differentiation and function | Experimental & Molecular Medicine Spi-C positively regulates RANKL-mediated osteoclast differentiation and function | Experimental & Molecular Medicine](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs12276-020-0427-8/MediaObjects/12276_2020_427_Fig1_HTML.png)
Spi-C positively regulates RANKL-mediated osteoclast differentiation and function | Experimental & Molecular Medicine
![Roles of the RANKL–RANK axis in antitumour immunity — implications for therapy | Nature Reviews Clinical Oncology Roles of the RANKL–RANK axis in antitumour immunity — implications for therapy | Nature Reviews Clinical Oncology](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41571-018-0095-y/MediaObjects/41571_2018_95_Fig1_HTML.png)
Roles of the RANKL–RANK axis in antitumour immunity — implications for therapy | Nature Reviews Clinical Oncology
![Frontiers | The Roles of RANK/RANKL/OPG in Cardiac, Skeletal, and Smooth Muscles in Health and Disease Frontiers | The Roles of RANK/RANKL/OPG in Cardiac, Skeletal, and Smooth Muscles in Health and Disease](https://www.frontiersin.org/files/Articles/903657/fcell-10-903657-HTML/image_m/fcell-10-903657-g002.jpg)
Frontiers | The Roles of RANK/RANKL/OPG in Cardiac, Skeletal, and Smooth Muscles in Health and Disease
A simple and robust reporter gene assay for measuring the bioactivity of anti-RANKL therapeutic antibodies - RSC Advances (RSC Publishing)
![PTH Differentially Regulates Expression of RANKL and OPG - Huang - 2004 - Journal of Bone and Mineral Research - Wiley Online Library PTH Differentially Regulates Expression of RANKL and OPG - Huang - 2004 - Journal of Bone and Mineral Research - Wiley Online Library](https://asbmr.onlinelibrary.wiley.com/cms/asset/516e3467-0259-4766-b59b-bf021525abf5/mfig002.jpg)
PTH Differentially Regulates Expression of RANKL and OPG - Huang - 2004 - Journal of Bone and Mineral Research - Wiley Online Library
![Receptor activator of nuclear factor-κB ligand (RANKL)/RANK/osteoprotegerin system in bone and other tissues (Review) Receptor activator of nuclear factor-κB ligand (RANKL)/RANK/osteoprotegerin system in bone and other tissues (Review)](https://www.spandidos-publications.com/article_images/mmr/11/5/MMR-11-05-3212-g00.jpg)